Project Title: Targeting pancreatic stellate cell activation
to direct new therapeutic strategies for pancreatic
ductal adenocarcinoma
Project Aims:
Pancreatic tumours often have a thick coat of fibrous scar tissue which blocks chemotherapy drugs and prevents the body’s immune system from stopping the cancer growth. By targeting this protective coating, this project aims to make pancreatic cancer sensitive to chemotherapy and also predict whether new immunotherapy treatments that work with other cancers can help with pancreatic cancer.