Dr Fieke Froeling
Project Title: Novel strategies for pancreatic cancer treatment: an epigenetic approach Project Aims: Dr Froeling‘s project will focus on ‘epigenetics’ – changes in DNA that can switch genes on and...
Diagnostics and imaging
...pancreatic cancer, finding biomarkers to detect the disease in urine or blood and new imaging techniques both for diagnosis and monitoring the effectiveness of treatments. UroPanc: validating a test for...
Professor Stephen Neidle
...shrank significantly in size. In a new study funded by PCRF, Prof. Neidle and his team aim to optimise this potential drug to be as active and efficient as possible...
Professor Marco Falasca
...role of a specific PI3K isoform p110 gamma in pancreatic cancer. Our hypothesis is that p110gamma overexpression is a frequent and early event in pancreatic cancer progression and could therefore...
Professor Martin Clynes
Project title: Investigation of miRNAs in human pancreatic cancer: functional role and potential therapeutic and diagnostic applications Project aims: Every cell in our bodies contain thousands of proteins whose job...
Dr Claire Wells
...family GTPases; Rho, Rac, and Cdc42. There is considerable evidence that Rac/Cdc42interacting proteins, the p-21 activated kinase family (PAK1-6), may play a key role in cell migration and regulation of...
Professor Hemant Kocher
...the medium to long term (5-10 years) to abrogate the abnormal FGF signalling. Thus if we can modify these local hormones to affect cancer growth and allow anti-cancer agents to...
Professor Caroline Dive
Project Title: Development of blood-borne biomarkers for improving treatment selection for pancreatic cancer patients Project Aims: Professor Dive and her team will analyse stray tumour cells that circulate in the...
Dr Eithne Costello
Project Title: Involvement of microRNAs in the activation of cancer-associated pancreatic stellate cells Project Aims: Pancreatic tumours are helped in their growth and spread by star shaped cells called pancreatic...
Fantastic young fundraisers, Amber and Edward
...walk next year, although her mum Andy says Amber hasn’t grasped the actual distance involved! Edward defied all expectations and walked the whole way without being carried, bravely pushing through...